Centre de Génétique Médicale de Gand Centre de Génétique Médicale de Gand

PhD fellowship vacancy in pediatric oncology

PhD fellowship vacancy in pediatric oncology

"Therapy response monitoring in pediatric cancer basket trial patients"

The position:

The cancer research team at the Center for Medical Genetics (cmgg.be) (supervised by prof. dr. ir. Jo Vandesompele, prof. dr. Tom Van Maerken, dr. Bram De Wilde) has an open PhD position in the domain of translational pediatric cancer research.

The project:

While global survival of children with cancer is reaching up to 80%, cure rates remain disappointingly low for certain high-risk types of tumors and for most relapsed cases. Novel treatment approaches are urgently needed to further improve survival but also to reduce long term side effects. Translating novel, targeted therapies from the lab to the clinic remains challenging; often promising pre-clinical data cannot be translated in therapeutic improvements for the children with cancer. In this project, you will use the power of modern genomics techniques (RNA sequencing) to facilitate this translation. By discovering tumor response expression signatures in both in vitro (cell lines) and in vivo tumor model systems (murine xenografts) we hope to find biomarkers of therapy response in children treated with targeted therapies.

Your profile:

You are a highly motivated, critical and curious researcher with a keen interest in translational cancer research, willing to work in an international and multi-disciplinary research context. What you might lack in experience you make up for in eagerness to learn and introduce new techniques.

What we offer:


Center for Medical Genetics Ghent (CMGG)
Medical Research Building 1
campus UZ Gent
Corneel Heymanslaan 10
B-9000 Ghent, Belgium
tel +32 9 332 24 51

Candidates can apply by sending their CV and letter of motivation to annelies2.depaepe@ugent.be before July 6th, 2018. Top-ranked candidates will be invited for an interview (either on site or via Skype). Start date is between Sept 1 and Oct 1, 2018.

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Post date: 05 juin 2018
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