Genomic Medicine is a rapidly developing science-driven approach to health care. It potentially holds great benefits for patients, clinicians, heal
En savoir plusPlease note, our postal address has been changed from De Pintelaan 185 - 9000 Gent to C. Heymanslaan 10 - 9000 Gent...
En savoir plusRecent gaf de BelMolGen werkgroep van de BeSHG enkele minimale richtlijnen (Download) uit inzake variant classficatie met tot doel het uniformiseren van de classificatie over de verschillende Belgische genetische centra en laboratoria. ...
En savoir plusDigital polymerase chain reaction (digital PCR, dPCR) is a direct nucleic acid quantification method, thus requiring no standard curves unlike quantitative real-time PCR (qPCR). Nevertheless, evaluation of the linear dynamic range, accuracy, and precision of an assay or platform is recommended, as there are several potential causes of important non-linearity, bias, and imprecision. Ignoring the...
En savoir plusAbstractHodgkin lymphoma (HL) is a malignancy of germinal center (GC) B-cell origin. To explore the role of long noncoding RNAs (lncRNAs) in HL, we studied lncRNA expression patterns in normal B-cell subsets, HL cell lines, and tissues. Naive and memory B cells showed a highly similar lncRNA expression pattern, distinct from GC-B cells. Significant differential expression bet...
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